Gladstone Institutes is an independent, nonprofit research organization driving a new era of discovery in disease-oriented science—an era in which it’s possible to contemplate cures, not just treatments.
Our mission is to drive a new era of discovery in disease-oriented science and to mentor tomorrow’s leaders in an inspiring and diverse environment.
Gladstone is located in San Francisco, surrounded by three world-class universities and at the epicenter of a thriving biotech and venture capital ecosystem. Our streamlined leadership structure and unique culture allow us to pursue the boldest scientific ideas as urgently as we can, to ultimately help as many patients as possible.
Gladstone By the Numbers
5 Institutes
33 Labs
660+
Gladstonians, including:
Two Nobel Prize Winners
Shinya Yamanaka
2012 Nobel Prize in Physiology or Medicine
Induced Pluripotent Stem Cells

Jennifer Doudna
2020 Nobel Prize in Chemistry
CRISPR-Cas9 Genome Editing Technology
8 Members of the National Academy of Medicine
Jennifer Doudna
Warner Green
Robert W. Mahley
Lennart Mucke
Katie Pollard
Deepak Srivastava
R. Sanders Williams
Shinya Yamanaka
Gladstone By the Numbers
5 Institutes
- Institute of Cardiovascular Disease
- Institute of Data Science and Biotechnology
- Gladstone-UCSF Institute of Genomic Immunology
- Institute of Neurological Disease
- Institute of Virology
33 Labs
660+
Gladstonians, including:
193
PhD Students and Postdocs
265
Scientists
141
Research Operations
Two Nobel Prize Winners
Shinya Yamanaka
2012 Nobel Prize in Physiology or Medicine
Induced Pluripotent Stem Cells
Jennifer Doudna
2020 Nobel Prize in Chemistry
CRISPR-Cas9 Genome Editing Technology
8 Members of the National Academy of Medicine
Jennifer Doudna
Warner Greene
Robert W. Mahley
Lennart Mucke
Katie Pollard
Deepak Srivastava
R. Sanders Williams
Shinya Yamanaka
Our
Gladstone is an administratively and financially independent nonprofit organization that enjoys a vibrant partnership with UC San Francisco, one of the nation’s premier health sciences institutions. Most of Gladstone’s principal investigators hold faculty positions at UCSF. Gladstone also has affiliations with UC Berkeley and Stanford University.
Our Impact
200+
Papers published in 2024 in scientific journals
5
Most highly cited researchers in the world in 2024
211
Patents
15
Start-ups founded by Gladstone scientists since 2015
$2.5B
Raised by Gladstone-backed start-ups from public and private financing
$28M
In commercially sponsored research in the last 5 years
Core Values
At Gladstone, the fundamental values of excellence, integrity, rigor, and respect are of the utmost importance, as they are in most great organizations. However, what makes Gladstone special is the set of core values that are perfectly aligned to our culture and guide our decisions.
Our
At Gladstone, we leverage cutting-edge technologies and data science to solve the most challenging biomedical problems. Our ultimate goal is to make a substantive impact on medicine and healthcare through our research. By combining the world’s top researchers in AI, stem cells, and gene editing with disease experts, we are driving toward a new class of curative and preventive therapies to overcome disease
Our
We encourage experts from different backgrounds to jointly tackle large problems and develop technologies needed to support our mission. We accelerate the pursuit of science by leveraging complementary scientific skills and exemplary administrative expertise. Above all at Gladstone, we champion highly interactive, creative, and innovative approaches to science as we seek prevention, treatments, and cures for major diseases.
$126M
Annual Operating Buget
Gladstone Institutes was established in 1979 through a generous donation from J. David Gladstone, who left his estate to support medical students interested in research. The trustees in charge of J. David Gladstone’s estate made some bold decisions to turn the original vision into something much larger that would have a huge global impact.
The Ogawa-Yamanaka Stem Cell Prize recognizes individuals whose original translational research has advanced cellular reprogramming technology for regenerative medicine. The prize was established in 2015 through a generous gift from the late Hiro and Betty Ogawa, and is supported by Gladstone Institutes and the Cell Press group. It also recognizes Gladstone Senior Investigator Shinya Yamanaka, who discovered induced pluripotent stem (iPS) cells.
Send Us a Message
Gladstone Institutes
1650 Owens Street
San Francisco, CA 94158
415.734.2000
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Gladstone Institutes
1650 Owens Street
San Francisco, CA 94158
415.734.2000
Getting Here
Media Inquiries
Contact an Investigator Directly